MGT-MKU

MGT - MKU

DISCOVERY

	1	Photosynthetic rhizobium
	2	PolyA containing RNA in cyanobacteria

INVENTIONS

HEALTH CARE

A. Nanoceutics (Nano- peptide therapeutics)

	1	Designer calcitonin a nanopeptide hormone, resistant to gut proteases
	2	Bioproduction of modified thymosin 4 to arrest cell proliferation
	3	Designer antimicrobial peptide “Parasin I”
	4	Designer antimicrobial peptide “Thanatin”
	5	Designer antimicrobial peptide “MGT-Lfcin”
	6	Designer antimicrobial peptide “virescein “
	7	Designer antimicrobial peptide “MGT-LLp20”
	8	Designer nanopeptide aptamer antagonist to cholesterol esterase
	9	Designer nanopeptide aptamer antagonist to pancreatic lipase
	10	Designer multiepitopic vaccine for rabies
	11	Designer wound healing nanopeptide MGT 100
	12	Designer wound healing nanopeptide msMGT3
	13	Designer nanopeptide antagonist for Phospholipase A2
	14	Designer Taxol pharomocophore capping nanopeptide
	15	Designer Mitomycin C pharmocophore capping nanopeptide

B. RNA therapeutics

Patent awarded
	1	Dr.Sambandam Shanmugasundaram, Mrs. Sri Lakshmi Seelam, Dr,(Mrs) Suguna Shanmugasundaram. Preparation of engineered bioactive peptide containing Alanine, Leucine, Tryptophan, Lysine, Asparagine, Isoleucine, Valine, Arginine aminoacids which is expressed in E. coli exhibiting anti microbial activity. [197940 - Filed 22.05.2003 and awarded 26.12.2005]
	2	Dr.Sambandam Shanmugasundaram, Parthasarathy Krupakar, Dr.Suguna Shanmugasundaram. Preparation of oligosaccharide bionanoparticles from Moringa oliefera, Lam [ 218499 filed on 05.05.2003: awarded on 02.04.08]
	3	Gorur Amita ,Dr.Sambandam Shanmugasundaram and Dr.Suguna Shanmugasundaram .Preparation of Agar Bionanoparticles. [222300-Filed 05.05.2003 and awarded 05.08.2008].

sncRNA plasmid against VEGFR 2

sncRNA plasmid against STAT 3

sncRNA plasmid against BCL 2

sh-RNA plasmid against PLD 1

shRNA plasmid against DNMT 3

INDUSTRIAL

Cyanozyme - cyanobacterial nuclease.

ISS (immuno stimulatory sequences ) from cyanobacteria

Preparation of antimitotic oligosaccharides

Recombinant staphylokinase

AGRICULTURE

Cyano-straw

Flexi-bioreactor for BGA cultivation

sncRNA plasmid against Helicoverpa armigera – Chitinase gene (Chi).

sncRNA plasmid against Helicoverpa armigera – Mono oxygenase (Shd).

sncRNA plasmid against C. elegans –Tyrosyl proteins sulfotransferase A gene

sncRNA plasmid against Mosquitoes – Chitin synthase gene (CHS-1).

Novel protocols developed

	1	Isolation of high molecular weight DNA of Gloeocapsa decorticans
	2	Preparation of gene bank of Gloeocapsa decorticans
	3	Preparation pf gene bank of Nostoc sp
	4	Preparation of gene bank of Anabaena sp
	5	Preparation of gene bank of Tolypothrix sp
	6	Preparation of gene bank of Westielopsis sp
	7	Preparation of highly phosphorylated adenine nucleotides from Tolypothrix sp.
	8	Genetic transformation of electro-competent cyanobacteria
	9	Preparation of cyanobacterial peptide toxins for use as biopesticides.
	10	Preparation of neurotoxin (parathions) detoxifying enzymes from cyanobacteria.
	11	Non radioactive assay of Kanamycin Phospho Transferase
	12	Preparation of agarose nanoparticles
	13	Preparation of chitin nanoparticles
	14	Preparation of bio-silica
	15	Preparation metal fulvates
	16	Preparation of fluro-liposomes
	17	Preparation of nano-curcumin
	18	Preparation of liposome stabilizing bio-surfactant
	19	Preparation of hydrophobic oligosaccharide nanoparticles
	20	Preparation of pectin nano-composites